Degradation and Kinetics Study of Enrofloxacin using Diperiodato Cuprate (III) in Alkaline Medium

Authors: Sangam SA* , Thabaj KA , Kulkarni RM and Mathad SN*

DOI: 10.23880/nnoa-16000223

Volume 7, Issue 3

Abstract

The antibiotic enrofloxacin is vitiated in an alkaline medium with diperiodatocuprate (III), and the reaction is monitored using an Ultra Violet Spectrophotometer at a wavelength of 415 nm with constant ionic strength and dielectric constant. At room temperature, varying the oxidant concentration while keeping all other variables constant results in pseudo first order kinetics. The sequence of the reaction is determined by altering the concentration of the antibiotic enrofloxacin at four different temperatures and the results are used to compute thermodynamic and activation values. Activation parameter, entropy increases on achieving the transition state and followed dissociative mechanism. Feasible reaction mechanism is proposed based on the probable products of oxidation and the active species of reactants. 

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