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"Kevin Francis" ×
AABSc Research Article Aug 22, 2023
Flavin Monooxygenases: A Multifaceted Class of Enzymes with Abundant Biomedical Applications
Madison Guess and Kevin Francis*

Flavin-dependent monooxygenases (FMOs) catalyze oxidation of a variety of organic molecules many of which have a profound biomedical applications. Oxidation occurs through the inco…

Flavin-Dependent Monooxygenases Flavin Adenine Dinucleotide Nucleotide Adenine Diphosphate
IJBP Review Article Aug 11, 2023
Targeting Redox Enzymes of Cholesterol Biosynthesis: A Step in the Right Direction Towards Ending Cardiovascular Disease
Taylor M Borah, Alexandria C Guerra and Kevin Francis*

Global occurrence of cardiovascular diseases is a serious health concern resulting in over 2 million deaths annually. A major cause of cardiovascular disease is elevated levels of…

Cholesterol Biosynthesis High and Low Density Lipoproteins 3-Hydroxy-3-Methylglutyl Coa Reductase
AABSc Research Article Sep 28, 2020
An Improved Protocol for the Expression and Purification of Tetracycline Monooxgenase: An Enzyme Involved in Antibiotic Resistance
Jennifer Bernal, Zainab Ojutiku, Adriana Cordero, AshLee Martinez, Kayle Berkey and Kevin Francis*

Tetracyclines are an important group of antibiotics used in agricultural and clinical settings. They function by binding to the 30S subunit of the prokaryotic ribosome to effectiv…

Protein Biochemistry Enzyme Expression And Purification Antibiotic Resistance