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Browse peer-reviewed articles from Medwin Publishers' open access journals.
Showing 1–3 of 3 articles
"Matsumoto K"
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How Bulky of Base Adducts can be Responsible for Clastogenicity
rather than Mutagenicity?
Two types of TK mutants are induced by genotoxic factors; normally growing (NG) TK mutants due to point mutations of targeted TK locus, and slowly growing (SG) mutants due to gros…
Bulky adducts
n-Alkyl methanesulfonates
Slowly growing TK mutant
Is Genotoxicity of Peroxisome Proliferator-Activated Receptor Agonists Due to Oxidative Stress Via Agonistic Pathways?
In order to investigate the relationship between genotoxicity and peroxisome proliferator-activated receptor (PPAR) agonistic effects, we conducted two kinds of comet assays (cell…
PPAR Agonist
PPAR Antagonist
Genotoxicity
Are Bases Alkylated by Branched Alkylating Agents Removed by
Nucleotide Excision Repair or Base Excision Repair?
We have shown that comet-positive responses by adducts that are repaired by nucleotide excision repair (NER) and base excision repair (BER) are reduced by α-amanitin (AMN) and enh…
mation of Comet Tails
NER
BER