Although the comet assay is now a popular method to assess DNA damage induced by environmental genotoxins at a single cell level, it has not been excluded the, criticism that some or all of the comet images may be the results of apoptosis- and necrosis-mediated DNA fragmentation. In this study, ther …
Crop rotation, one of the oldest agronomic practices known to humanity, continues to be debated in the context of modern intensive farming systems. As agriculture has shifted toward monoculture-dominated landscapes driven by economic and logistical pressures, the incidence of soil-borne and foliar d …
Background: Rapamycin (sirolimus), originally isolated from Streptomyces hygroscopicus, is a macrolide compound that has profoundly influenced modern biomedical research through its inhibition of the mechanistic target of rapamycin (mTOR) pathway.
Objective: This review aims to synthesize current …
Hypogonadotrophic hypogonadism, which is characterized by low serum testosterone co-existing with elevated Luteinizing hormone (LH) and Follicle stimulating hormone (FSH) has been reported to be a common finding in poorly managed diabetes mellitus (DM). This study is an attempt to investigate the im …
Bupropion, a monocyclic phenylethylamine antidepressant, is the only FDA-approved synthetic cathinone, commonly prescribed as monotherapy or adjunctive therapy for major depressive disorder, seasonal affective disorder, and smoking cessation. Although traditionally considered non-serotonergic, bupro …
Over the last several decades, the nanotoxicology of zinc oxide nanopaarticles (ZnO-NPs) has remained a debate topic in scientific community. Even though many researchers have attempted to elicit the mechanisms of ZnO nanotoxicity, their potential hazardous impact on humans, animals, and the environ …
As a young general practitioner, I started a medical group in North Limburg in 1977. In this region, along the Albert Canal and the Kempen Canal, many non-ferrous factories had established after the conquest of Congo at the beginning of the last century. The ores arrived from Congo in the port of An …
