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L-Arginine is a semi-essential amino acid in human that is considered as one of the most metabolically versatile amino acids. It serves as a precursor for the synthesis of nitri…

X-linked centronuclear myopathy (XLCNM) is a rare disease which sometimes is accompanied by extramuscular complications. We report a 15 month old boy with XLCNM and hepatic failure…

Objective: The comprehensive review is prompted by a scarcity of consolidated information, about persistent diarrhea that is a matter of concern for all involved in child health. R…

Phosphodiesterase-5 (PDE5), receptor for the drugs sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis), selectively hydrolyzes the second messenger cGMP. How…

This study investigates the function of 5-HT type 3 (5-HT3) receptors using a computational approach. Antagonists of the 5-HT3 receptor are currently one of the most effective ther…

Objective: Our objective is to study the possible role of low dose sevelamer hydrochloride on the rate of progression of coronary artery calcification among prevalent hemodialysis …

The Synovial Sarcoma (SS) is a rare neoplasm, the fourth most common type of sarcoma. Most often located at the para-articular region of inferior limbs and tendons. Renal presentat…

Matching the treatment intensity with the severity of asthmatic symptoms is the basic treatment for asthma. Intermittent treatment with rapid symptom relief should be administer…

Fragmentation of therapeutic monoclonal antibodies (mAbs) is a critical quality attribute (CQA) that needs to be monitored and controlled during the biopharmaceutical drug developm…

During the aging process occur several changes, among them the increased weight and obesity contribute to the health risk potential of this population. Bringing losses as disabilit…

Objective: To evaluate oncologic outcomes in clinical T1a tumors which remain pathological T1a compared to tumors which were upstaged to pathologic T3a due to perirenal fat invasio…

An evaluation trial conducted over 30 years on coconut hybrid combinations has resulted in identification of a superior, high yielding Tall x Tall hybrid, released as VPM 5 involv…

The role of sleep on human health has been largely underplayed till the 60’ when the first papers appeared, but the true advancement in this field came at the end of the past ce…

To match the driving voltage (3-5 V) of the driving circuits on silicon, we report an organic light-emitting device on silicon substrate featuring low turn-on voltage, high brightn…

Background and aims: The role of sphincter of Oddi dysfunction (SOD) and sphincter of Oddi manometry (SOM) in patients with post-cholecystectomy pain and idiopathic recurrent acute…

Magnesium participates as essential cofactor in the vast majority of the enzymatic process related with energetic metabolism furthermore, emerging clinical evidences show that m…

Nowadays, uterine artery embolization (UAE) is a widely acceptable non-surgical procedure appropriate for selected patients with uterine myomas [1-6]. It is based on a well-esta…

Background: Breast cancer is the most common cancer in women globally as well as the principle cause of death. Despite the high incidence rates of this malignant disease, 89% of w…

Aim: The aim of the study was to assess dietary diversity score and nutritional status of rural adult women in Abia State, Nigeria. A sample of 240 women was selected using simple…

Brazil has extensive biodiversity in their biomes, where the Cerrado, vegetation of the Brazilian interior, contributes a nutritional and medicinal potential still unexplored. The…

The structural/functional properties of albumin play an important role in the pathogenesis of various diseases (e.g. diabetes mellitus). In different pathologies membrane damage…

Diabetes is a chronic disease with high morbi-mortality and has been considered in the entire world a public health problem. Type 2 diabetes mellitus (T2DM) that accounts up to 95%…

Background: Insulin therapy refusal is a common subject in the routine of endocrinologists. New therapeutic options can work around this issue. Objective: To report a case of insu…

Liver is the major organ responsible for the maintenance of glucose homeostasis under fasting conditions. Hepatic gluconeogenesis is tightly regulated by the complementary actio…

The emergence of antimicrobial drug-resistant bacteria and their dissemination in the community represents a real challenge to Public Health, both today and for the years ahead. An…

Pig farmers in the informal settlements of Nairobi Kenya were interviewed to evaluate the use and possible effects of polluted river water on the reproduction of their boars. 80 fa…

The current study is a companion piece of an earlier study by Colburn published in August 1983 Issue of the Journal of Pharmacokinetics and Biopharmaceutics; therefore the data pub…

The prevalence of asthma is rising worldwide with 10–12% adults and 15% children affected presently. It can have a considerable impact on the quality of life of both, patients and…