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Exploratory Proteomic Profiling of SARS-CoV-2 Infected THP-1 Macrophages Reveals Alterations in Inflammatory Response and Cellular Metabolism

Macrophages are key players in innate immunity and inflammation during viral infections, including COVID-19. This study explored the cellular and proteomic responses of THP-1-deriv…

Inhibition of Snake Venom Serine Proteases Activities by Specific Antibody

According to the World Health Organization, snake envenomation is a major neglected public health problem. In addition to deaths, these accidents cause other severe disabilities, s…

Snake Envenomation: A Component- Based Review on Hemostatic Alterations

Considered by the World Health Organization a neglected public health problem, snakebites occur predominantly in tropical areas of Africa, Asia and Latin America. Approximately 2.…

THP-1-Derived Dendritic Cells: A Rapid and Reproducible In Vitro Model for Phagocytosis Assays Involving Tumor Cells

Dendritic cells (DCs) play a vital role in antigen-specific adaptive immunity by serving as sentinels, recognizing and presenting specific pathogenic peptides. Herein, we develop…