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"Leclerc M" ×
VVOA Research Article May 30, 2024
Comparative 3D Modeling of Anti-HRP Sea Star Primitive Antibodies and Their Relationships with Mus Musculus Fab
Leclerc M*

Presentations of sea star primitive antibody 3D modelizations, according AlphaFold and Swiss Model predictions were performed in EMBL Grenoble a superposition of the 2 predictions …

Sea Star Mus Musculus Antibodies
AII Research Article Feb 24, 2024
Determination of the CDR (CDR1, CDR2) « Complementary- Determining Region Invertebrate Primitive Antibody from Sea Star »
Leclerc M*

The IPA (Invertebrate Primitive Antibody) was recently discovered, in the same time of Asterias rubens lymphocytes, humoral specific immune responses and Genomic assays with the se…

Invertebrates Invertebrate Primitive Antibody CDR1
VVOA Opinion Nov 7, 2023
The Sea Star B Lymphocyte
Leclerc M*

The sea star B lymphocyte is found in the sea star axial organ which has been considered by us, as an ancestral lymphoid organ. Other lymphocytes are supposed to be also present…

Sea Star B Lymphocyte Endoplasmic
AII Short Communication Jun 20, 2022
Evidence of Sea Star Monocytes Evolving in Phagocytes: Asterias Rubens T.E.M Observations
Leclerc M*

Sea star Axial organ (A.O) cells were observed in T.EM: Evidence of primitive monocytes was done: They contained azurophile particles and a reniform nucleus, sometimes a phagosome…

Invertebrates Sea Star Monocytes
AII Short Communication Feb 23, 2022
Hla-E Gene from Ophiocomina Nigra (Echinodermata-Invertebrates) Bioinformatics Data
Leclerc M*

HLA-E gene from MHC (Major Histocompatibility Complex) system has been recently discovered, in our laboratory, in Invertebrates. Blasts were performed against different protein sp…

Chromosome Homologies
AII Short Communication Dec 13, 2021
A Sea Star Asterias Rubens IGKappa Gene when Compared to 3 Other Sea Star Genomes from Patiria Miniata, Acanthaster Planci and Marthasterias Glacialis (Echinodermata)
Leclerc M*

The sea star IGKappa gene was cloned in 2014 by the use of primers. It was compared, in the present work, to 3 other sea star genomes: Acanthaster planci, Patiria miniata and Mart…

Gene IGKappa Bioinformatic Analysis
AII Short Communication Nov 18, 2021
The Asterias Rubens Sea Star Igkappa Gene When Compared to Marthasterias Glacialis Sea Star Genome(Echinodermata)
Leclerc M*

The sea star IGKappa gene was cloned in 2014 by the use of primers. It was compared in the present work to Marthasterias glacialis sea star genome. A high identity was found with …

Asterias Rubens Echinodermata Human Genes
CCLSJ Research Article Jan 3, 2018
Adaptative Immunity, A True New Gene in Ophiocomina Nigra: An Ophuirid Igkappa Gene
Leclerc M*, Marie Y, Davoult D, Jolly A and de la Grange P

<p>It was shown 32 years ago that the sea star axial organ cells (AO cells) produced a spontaneous cytotoxicity against mouse cancerous cells. Recently, we discovered a sea s…

&lt p&gt Ophiocomina Nigra
CCLSJ Mini Review Oct 20, 2017
The Sea Star Ig Kappa Gene and Cancerology
<p>Leclerc M*</p>

It was shown 32 years ago that the sea star axial organ cells (AO cells) produced a spontaneous cytotoxicity against mouse cancerous cells. Recently, we discovered a sea star Ig ka…

<p>Ig Kappa Sea Star Organ Cells
CCLSJ Research Article Jun 19, 2017
Immunocytochemical Reactions in the Brittle-Star: Ophiocomina Nigra after Immunization
Leclerc M*, Henrik S and Bodil H

&lt;p style=&quot;text-align: justify;&quot;&gt;Immunizations of Ophiocomina nigra were performed with either Bovine Serum Albumine (BSA) or Horse-Radish Peroxydase (HRP) in aquari…

&lt p&gt Immunizations
CCLSJ Short Communication Feb 18, 2017
DNA Repair in Sea Star Asterias Rubens: Genomic Aspects
Leclerc M*

&lt;p&gt;In the present paper, we study the DNA repair through the animal kingdom and especially in the sea star system. Rad 51 family, found in Drosophila was shown in sea star ge…

&lt p&gt DNA repair genes
CCLSJ Short Communication Dec 29, 2016
Evidence of CR Receptor Gene in an Invertebrate
Leclerc M* and Kresdorn N

In 2013, Complement components were found in the Asterias rubens genome, when compared to mouse genome (Classical and alternative components). Recently, we discovered a Fab gene a…

CR receptor gene Sea star primitive antibody Invertebrate
PhIJ Investigation Paper Feb 3, 2023
The Second Person in Dialogue
Leclerc A*

first present a conception of the relata involved in the dialogic relation. I and thou are persons endowed with a first-person perspective and concepts through which they can repre…

Dialogic relation Perlocutionary plans Epistemology
CCLSJ Research Article May 2, 2017
The Sea Star Igkappa Gene and its Applications in Cancerology
Michel Leclerc*

&lt;p&gt;It was shown 32 years ago that the sea star axial organ cells (AO cells) produced a spontaneous cytotoxicity against mouse cancerous cells. The axial organ is considered a…

CCLSJ Mini Review Feb 18, 2017
Evidence of Complement Decay-Accelerating Factor Transmembrane Isoform Gene of Complement Factor B of Complement Factor H Genes in the Sea Star Asterias Rubens: Three Regulators of Complement Pathways
Michel Leclerc*

&lt;p&gt;The main components of Complement (alternative and direct pathway genes)correlated with mammal genes were discovered in the sea star genome. CR receptor gene was also foun…

&lt p&gt CR receptor gene