Discover Research Beta
Browse peer-reviewed articles from Medwin Publishers' open access journals.
Showing 1–11 of 11 articles
Although the comet assay is now a popular method to assess DNA damage induced by environmental genotoxins at a single cell level, it has not been excluded the criticism that some …
Our study using the comet assay to detect genotoxicity of carcinogens in multiple mouse organs reveled that the correlation between genotoxicity and carcinogenicity on an organ-by-…
It is important to know whether the DNA initial lesions are repaired or derive into chromosome aberration, gene mutation and/or cell death to discuss chemical carcinogenicity. To k…
The genotoxicity of pro-mutagens has been traditionally detected by test procedures with metabolically incompetent cells requiring addition of exogenous activation mixtures, such a…
Two types of TK mutants are induced by genotoxic factors; normally growing (NG) TK mutants due to point mutations of targeted TK locus, and slowly growing (SG) mutants due to gros…
In order to investigate the relationship between genotoxicity and peroxisome proliferator-activated receptor (PPAR) agonistic effects, we conducted two kinds of comet assays (cell…
We have shown that comet-positive responses by adducts that are repaired by nucleotide excision repair (NER) and base excision repair (BER) are reduced by α-amanitin (AMN) and enh…
Arsenic exists widely in the environment, and a lot of arsenic pollution is found in the groundwater of South East Asia. In order to make arsenic free water, we made a simple devi…
Portulaca (Portulaca oleracea cv.) is a popular floricultural herbal plant, and has a high ability in phytoremediation of various organic contaminants. The roots of portulaca rapi…
Under the recent trend of rapid increase of overseas travelers in Japan, the potential risks of visitors to the human tumor virus infections (HTLV-I, high –risk HPVs, HBV, HCV an…