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Medicinal & Analytical Chemistry International Journal

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Guohui Li

Guohui Li

Editorial Board Member
University of Florida USA Member since 2017

Biography

I was awarded my PhD degree in University of Hong Kong majored in biological mass spectrometry in 2015. During my PhD study, I have developed my expertise in mass spectrometry especially for its application on novel drug discovery from natural products by a metabolomics approach. I have built up a mass spectrometry based multivariate data analysis-guided fractionation strategy for lead compounds discovery from natural products with therapeutic effect for Parkinson’s disease, by which a novel natural neuroprotective lead compound_oxphylla A has been characterized and a related US patent has been granted. The underlying NRF2/HO-1 pathway was identified by proteomics approach to be involved in the mechanism of action for this compound. What’s more, I am also skilled at isolation and structural characterization of chemical components from traditional Chinese medicine. And now, I am working as an Adjunct Assistant Scientist in the Department of Chemistry, University of Florida. Till now, 20 peer-reviewed journal papers and 9 conference abstracts have been published and two invention patents were granted.

Research Interests

Mass spectrometry-based metabolomics Naturally occurring lead compounds discovery Natural medicinal chemistry

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