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Two types of TK mutants are induced by genotoxic factors; normally growing (NG) TK mutants due to point mutations of targeted TK locus, and slowly growing (SG) mutants due to gros…

In order to investigate the relationship between genotoxicity and peroxisome proliferator-activated receptor (PPAR) agonistic effects, we conducted two kinds of comet assays (cell…

Cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis are characterized by bile duct inflammation and damage followed by obstruction or …

Wildlife management represents an increasing challenge in Mediterranean ecosystems. Biodiversity conservation must be reconciled with agricultural activities, public safety, and …

organelles, establishing a strict conceptual dichotomy between phase-separated liquid droplets and classical lipid-bound compartments. Today, that dichotomy has broken down. The m…

Author presents three cases of epithelioid cell granuloma with different pathogenic backgrounds. Two cases were noninfectious and were diagnosed as lupus miliaris disseminatus fac…

A case of 22-year-old man with atopic dermatitis (AD) who developed concurrent psoriasis vulgaris (PSO) is presented. PSO is primarily mediated by T-helper (Th) 17 immune response…

The covert psychopath is a compensatory mode of psychopathy, reactive to a state of collapse (inefficacy in obtaining goals). An avalanche of misinformation online by self-styled …

Anemia, a prevalent hematological condition characterized by decreased red blood cell count or hemoglobin levels, has emerged as a significant risk factor for cerebrovascular acci…

The advancement of molecular methods resulted in the application of molecular xenomonitoring (MX) as a complementary tool to detect the presence of circulating LF parasites in mos…

We did not observe high values of cardiac markers and changes in central hemodynamic parameters in patients with acute gastrointestinal bleeding (AGIB) and a correlation between t…

This paper introduces the Mind the Gap Metacognitive Program (MGM-P), an innovative rehabilitation approach to contrast and prevent anosognosia. Anosognosia, or impaired self-awar…

Background: Low back pain is the most common type of pain. The causes of many painful conditions of the low back remain obscure. Low back pain bothers not only patients but also t…

In this article, the author discusses the benefits of grounding strategies in modulating arousal and emotion. These essential resources are reminders of the present and are well-us…

A case of pustulosis palmaris et plantaris or palmoplantar pustulosis (PPP) accompanied by generalized skin eruption is presented. Extra-palmoplantar skin lesions similar to those…

Animals in zoos are kept under environmental conditions differing from those of their original habitat. Recently, zoos have been attempting to reduce stress by introducing environ…

We have shown that comet-positive responses by adducts that are repaired by nucleotide excision repair (NER) and base excision repair (BER) are reduced by α-amanitin (AMN) and enh…

Background: This study aimed to assess the reliability of the posterior condylar axis (PCA), the most widely used alternative reference for the surgical transepicondylar axis (sTEA…

People with cerebral palsy often have sleep disorders, such as difficulty falling asleep or waking up often during the night, due to their physical disabilities. The main method o…

The Marine Program, which takes advantage of nature in Okinawa, was offered to children with neurodevelopmental disorders (NDDs). This study examined the effectiveness of the regu…

Suppurative appendicitis is an acute inflammatory reaction of the ileocecal appendix of an infectious etiology and it can result in complications and death if treatment is not star…

We must always be cautious about reactions that can cause severe, irreversible deformities when treating leprosy. We studied the clinical course of two patients with subpolar lepr…

Pipe depulsators are preliminary gas separation devices (PGSD). Professor E.P. Zaporozhets, the author, developed alternative depulsators – Autonomous Venturi nozzles (AVN) and …

The clinical course of leprosy varies depending on the level of host cell-mediated immunity to the causative agent, Mycobacterium leprae. In this study, the diagnostic aspects of t…

Restorative justice underlies various legal solutions all over the world. The Polish legislator also made reference to restorative justice by including the settlement between the …

Huntington’s Disease (HD) is an autosomal dominant neuropathology associated with severe degeneration in neurons of the basal ganglia. It is characterized by progressive motors sy…

Japan has long had a Leprosy Prevention Law. The experience of compulsory segregation often damaged patients’ selfesteem, causing most to break off their family relations. Even …

Purpose: There is no gold standard to diagnose lactose malabsorption. The hydrogen breath test is the most widely used, but many methodological points need to be standardized. Our …

Background: Sunitinib, an oral multi-targeted tyrosine kinase inhibitor has been approved for the treatment of advanced pancreatic neuroendocrine neoplasms (pNENs). Aim: To describ…

True psychotherapy does not involve helping clients “feel better” in a false way by providing any kind of consoling distracting escape from the actual experiential truth of them. …