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Cell & Cellular Life Sciences Journal

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Marisa M Merino

Editorial Board Member
University of Geneva Switzerland Member since 2022

Biography

Marisa Martinez Merino always been passionate to understand how cells within tissues communicate to build up successful organisms. Indeed, during her PhD work she found that, Cell Competition is a physiological mechanism which controls organismal lifespan. The difference between unfit and fit cells can be encoded by different levels of Dpp signaling. In the wing of flies and the pectoral fin of fish, the decay length of these morphogen gradients is proportional to the length of the growing tissue during development, namely they scale. Different levels of Dpp signaling are reminiscent of the steepness of the gradient that is its decay length. In her recent work, she has found of a novel phenomenon, Death mediated scaling: the scaling of TGF-beta type growth factors is mediated also by Cell Death. On the other hand disrupted TGF-beta signaling is one of the most common causes of tumor genesis.

Research Interests

Drosophila Cell Death Gradient Tumours Scaling Cell Fitness Quantitative Biology Biophysics

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