Josep M. Argiles was born in Barcelona, Catalonia, Spain in 1956 and completed his undergraduate studies in Biology at the University of Barcelona graduating with a First Class Honours Degree and Special Prize for the best B.Sc. (1979). In 1981 he received his Doctorate in Biochemistry from the same university with Cum Laude obtaining the Prize for the best doctorate of that year. He then became Lecturer in Biochemistry and carried out postdoctoral work on acetone metabolism in mammals. In 1987 he undertook further postdoctoral training in the Laboratory of Metabolism and Molecular Biology at the National Institutes of Health, Bethesda, Maryland. In 1988 he went to the Metabolic Research Laboratory, Radcliffe Infirmary, Oxford, UK to work on the metabolic effects of cytokines. He later became Full Professor of Biochemistry and Molecular Biology of Cancer at the Faculty of Biology, University of Barcelona being the leader of a research group interested in cancer cachexia. He has authored and co-authored over 350 publications, including several books, many related to the field of cancer research. He reviews scientific articles for over 90 international journals. Indeed, he was the first scientist to describe the mechanism responsible for the increased protein breakdown in skeletal muscle of cancer patients which seems to be responsible for muscle wasting.
Contributions in the form of pre-clinical studies regarding the pharmacological treatment of cachexia using different therapeutic startegies such asï€ ï¢2-agonists or anabolic cytokines and such as IL-15
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