Medwin Publishers | Aravinthkumar Jayabalan - International Journal of Biochemistry & Physiology

Aravinthkumar Jayabalan

Associate Editor

Johns Hopkins University USA Member since 2022

Biography

Aravinthkumar Jayabalan research career focuses on identifying the molecular mechanisms involved in the formation of one of the RNA/protein-rich biomolecular condensates in the cytoplasm called Stress Granules (SGs). A variety of factors are essential to maintain regular SG dynamics, including post-translation modification—conjugation of small peptides on target proteins. In his PhD research, he identified that NEDDylation—the addition of NEDD8 onto target proteins—plays a crucial role in SG assembly during oxidative stress. Proper SG dynamics is essential to keep the cells alive and any dysregulation in SG dynamics leads to a variety of diseases such as cancer, viral infection, and neurodegeneration. For example, SGs are usually a common target by many viruses during the late stages of infection—the mechanism behind is largely unknown. Therefore, delineating the molecular driving forces involved in SG dynamics during viral infection is thus crucial for developing broad-spectrum antiviral therapeutics.

Research Interests

Biomolecular Condensates RNA Granules Cellular Stress Response ADP-Ribosylation Translation Alphaviruses Macrodomain RNA Viruses Single-Molecule Imaging

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Vijaykumar Chollety

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Yuan Gu

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Kun Liu

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Alphonse Laya

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Azzeddine Charef

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Tariq Ahmad

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Hatice Yorulmaz

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Qenan Maxhuni

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Kuanlin Wu

Yale University

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Wei Chen

Shanghai University of Traditional Chinese Medicine

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Kai Huang

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Danielle Sandra

University of Pretoria

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Sandra Tatchum

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Ryan Adnan Sheikh

King Abdulaziz University

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Hongjin Zheng

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Omeed Darweesh

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Rukiye Oztekin

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Samer Y Alqaraleh

Mutah University

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Yanju Lu

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Xuemei Wen

The University of Texas at Austin

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Rini Bhatnagar

University College Dublin

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Lanza Giuseppe

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Abderrahim Nemmar

United Arab Emirates University

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Bing Yao

Nanjing University

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Aizman Roman Idelevich

Novosibirsk State Pedagogical University

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Athar Ansari

Wayne State University

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Vishwa D Trivedi

Bethune Cookman University

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Laping He

Guizhou University

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Gaoyuan Wang

Yale University

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Tharun Sundaresan

Uniformed Services University

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Shirani Ranasinghe

Manipal University College of Malaysia

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Chenshu Liu

University of California

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German L Velez Reyes

University of Minnesota

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Yu Chen

University of California

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MD Ashraful Islam

University of Tabuk

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Amit Kumar Verma

University of Wisconsin-Madison

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Pradeep Kumar Prabhakar

University of Georgia

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Alfi Sophian

National Agency of Drug and Food Control

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Abhijit Aithal

University of Nebraska Medical Center

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Ivan Chicherin

M V Lomonosov Moscow State University

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Claudia Andrea Lima Cardoso

Universidade Estadual de Mato Grosso do Sul

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Jin Xu

University of Maryland Baltimore

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Zeng Hui Diao

Zhongkai University

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Takao Imai

Keio University School of Medicine

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Mahira Amirova

Azerbaijan Medical University

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Yuwaraj Narnaware

MacEwan University

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Sebastiao David Santos Filho

Federal University of Rio Grande do Norte

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Siti Fatimah Ibrahim

Universiti Kebangsaan Malaysia

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Joice Margareth de Almeida Rodolpho

Federal University of Sao Carlos

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Olga V Akopova

Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine

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Mohammed Kabir Uddin

North South University

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Sanjay Mishra

SR Institute of Management & Technology

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Ashok V

Sri Balaji Vidyapeeth University

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International Journal of Biochemistry & Physiology

Aravinthkumar Jayabalan

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